Over the past 8 years, over 150 runners, walkers and triathletes from around the US, Canada, Australia and the world have crossed finish lines of races ranging from a 5K to the Ironman and raised over $150,000 in the process for FAST as part of Team Miles for Smiles. Because of recent advancements in the understanding of AS, treatments for this disorder are not only possible, they are probable.Individuals with AS typically have balance issues, motor impairment and debilitating seizures. Some patients never walk. Most do not speak. Despite its often devastating effects, Angelman syndrome is a simple disorder involving only one gene. FAST scientists have already cured AS in the lab using several different approaches. FAST is committed to bringing life-changing treatments for Angelman syndrome to clinical trial within two years – but we need your help. FAST has brought together a multi-disciplined team of more than two-dozen scientists from multiple universities and pharmaceutical companies to join forces on a focused path to a cure. I'm inspired by the breakthroughs being made by FAST, and I want to do my part by raising money to fund clinical trials for Angelman syndrome (AS). FAST researchers know exactly what causes AS and have already cured it in the laboratory. Today, five therapy strategies are in development to treat Angelman syndrome. Your donation to my page helps fund all of them. Please help me support this critical research by clicking the “Give Now” button and donating whatever you can. Every single dollar counts and is appreciated! The more people that know about FAST, the greater their impact, so please also spread the word by sharing my page with your contacts. Since AS is a rare disorder, we truly rely on the support of friends and family members to fund this groundbreaking research. Thank you in advance for your generosity.Their work will change life for people with Angelman syndrome and, potentially, related disorders like autism and Alzheimer’s disease. FAST is the largest non-governmental funder of Angelman syndrome research and the only organization with a detailed plan towards a cure. To learn more about Team Miles for Smiles, to become involved and set a race as a fundraising goal for this amazing organization, or to be partnered with an Angel and their family as part of our Wings to Fly partnership, please visit the Miles for Smiles website at http://www.miles-for-smiles.org/.